The Kentucky Health Information Exchange (KHIE) is the public health authority for meaningful use reporting in Kentucky. Kentucky eligible professionals (EPs) and eligible hospitals/critical access hospitals (EH/CAHs) who wish to submit data to any of the following registries must do so through KHIE:

Kentucky Immunization Registry

Any EP or EH/CAH that administers any type of immunization (influenza, pneumococcal, HPV, chickenpox, shingles, etc.) during the EHR reporting period can submit to or query the immunization registry.

CDC BioSense Syndromic Surveillance

In Kentucky, all EPs or EH/CAHs collect syndromic surveillance data.

Kentucky Cancer Registry

Any EP who diagnoses and/or treats cancer patients can submit to the Kentucky Cancer Registry.

KHIE Advance Directive Registry

In Kentucky, any EP or EH/CAH can submit advance directive documents to the KHIE Advance Directive Registry.

Kentucky National Electronic Disease Surveillance System

Kentucky recently adopted legislation, 902 KAR 2:020, requiring laboratory results to be reported electronically to KHIE.

Kentucky Health Information Exchange

Any EP or EH/CAH can use KHIE as a clinical data registry for meaningful use stage 3. 

To register your intent to submit to any of these registries contact


Public Health and Clinical Data Registry Reporting for EHR Incentive and Quality Payment Programs


Kentucky Health Information Exchange Services in 2017


Kentucky Administrative Regulation - Electronic Laboratory Reporting

Effective October 2016, Kentucky Administrative Regulation 902 KAR 2:020 requires Kentucky health care providers to electronically submit reportable diseases to the Kentucky Department for Public Health via KHIE.

To get into the queue and be onboarded to KHIE for electronic laboratory reporting, providers must meet the following conditions:

  1. Providers must have a signed participation agreement and a disease surveillance addendum with KHIE.
  2. Laboratory feeds and reference lab orders and results must be fully mapped to Logical Observation Identifiers Names and Codes and Systematized Nomenclature of Medicine, with the exception of HIV- and AIDS-associated laboratory reports.
  3. The established all-inclusive laboratory data feed must contain HL7 2.5.1 ELR Standard Unsolicited Observation or Unsolicited Lab Observation messages from a 2014 certified electronic health record system.
  4. An established all-inclusive admit, discharge and transfer feed.

These requirements aim to simplify hospital responsibilities, ensure ongoing compliance with state regulations on meaningful use, adhere to KHIE methodological framework and prevent inadvertent submission of conditions prohibited from being delivered to Kentucky’s National Electronic Disease Surveillance System (NEDSS). KHIE will monitor the all-inclusive laboratory feed and automatically forward disease surveillance data to Kentucky NEDSS in accordance with state regulation.

Kentucky Unbridled Spirit